Yale E. Goldman

Research Interests

My lab studies molecular motors, protein synthesis on the ribosome and RNA helicases using novel biophysical techniques. We develop new methods particularly in single molecule biophysics, such as fluorescent particle tracking, high-speed optical traps, and polarized total internal reflection fluorescence (polTIRF) microscopy to quantify the structural dynamics of rotational motions of the target proteins and to delineate the mechanisms of enzymatic and energy transformation reactions.