Molecular & Cellular Biology

Plant Cell Structure Could Hold Key to Cancer Therapies and Improved Crops

Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The proteins that give plants their shape and structure are also involved in human disease. A team led by researchers at the University of California, Davis, has mapped out the structure of a key player, augmin, in exhaustive detail.

Mirror Image Pheromones Help Beetles Swipe Right

There are many ways to communicate with prospective romantic partners: If you are a Japanese scarab beetle, it’s a matter of distinguishing left from right. New work from U.S. and Chinese scientists, published this week in Proceedings of the National Academy of Sciences, shows how these beetles use mirror-image pheromones to find a mate. The work could lead to better monitoring and control of significant agricultural pests.

Tiny Engines Provide Energy for Life, Mapping Them Could Help Us Treat Genetic Disorders

Inside our cells are tiny engines that supply the energy to sustain life. These protein machines essentially burn our food – producing CO2 and harnessing the energy that is released to sustain growth, movement and even thought.

Each year, roughly 1.6 million people worldwide are born with genetic diseases that disrupt these tiny cellular engines – making life difficult.

“Mutations in these protein complexes are really devastating, and often lethal,” says James Letts, an associate professor of molecular and cellular biology. 

Worms Reveal Just How Cramped Cells Really Are

In a new study published in Science Advances on September 10, a team of UC Davis researchers tracked the movement of fluorescent particles inside the cells of microscopic worms, providing unprecedented insights into cellular crowding in a multicellular animal. They found that the cytoplasm inside the worms was significantly more crowded and compartmentalized than in single-celled yeast or mammalian tissue culture cells, which are more commonly used to gauge internal cellular dynamics.

This Snail’s Eyes Grow Back: Could They Help Humans do the Same?

Human eyes are complex and irreparable, yet they are structurally like those of the freshwater apple snail, which can completely regenerate its eyes. Alice Accorsi, assistant professor of molecular and cellular biology at the University of California, Davis, studies how these snails regrow their eyes — with the goal of eventually helping to restore vision in people with eye injuries.

CBS Dept. and Grad Group Faculty Elected as AAAS Fellows

Three faculty affiliated with the College of Biological Sciences are among the eight UC Davis faculty newly elected as fellows of the American Association for the Advancement of Science, announced March 27. They are: Frédéric Chédin, a professor and chair in the Department of Molecular and Cellular Biology; Dario Cantù, a professor in the Department of Viticulture and Enology; and Huaijun Zhou, a professor in the Department of Animal Science.